Friday, September 24, 2010

Nightshades and Down Syndrome. Dammit, I KNEW IT!!!

This is really pissing me off, seriously.  If I can find this connection . . . why the F can't the western medical community find it???  And do they listen to me when I try to tell them??  Noooooo . . . I don't have a medical degree, let alone a degree past an AA from a community college.  That doesn't mean I'm not smart or thorough, just that I personally found college to be a waste of my time and money.  But that's a different subject . . .

I found the connection today . . . it's out there . . . already known . . . just nobody's put the two together.  I was doing some more reading about the Paleo Diet (which Kaiden is on) to get the specifics of why nightshades aren't part of the Paleo Diet.  For one, they are considered a "New World food", meaning they were not available to our early ancestors, so therefore they were not eaten.  Now this website: http://www.eczemacure.info/blog/2010/06/14/paleo-diet-potatoes-leaky-gut-and-other-autoimmune-disease/, talks about potatoes (a nightshade food) and how the alkaloids do damage:

"Potatoes contain two glycoalkaloid saponins: ?-chaconine and ?-solanine which may adversely affect intestinal permeability and aggravate inflammatory bowel disease11, 12. Even in normal healthy adults, a meal of mashed potatoes results in the rapid appearance of both ?-chaconine and ?-solanine in the bloodstream13. The toxicity of these two glycoalkaloids is dose dependent – meaning that the greater the concentration in the bloodstream, the greater is their toxic effect. At least 12 separate cases of human poisoning from potato consumption, involving nearly 2000 people and 30 fatalities have been recorded10. Potato saponins can be lethally toxic once in the bloodstream in sufficient concentrations because these glycoalkaloids inhibit a key enzyme (acetyl cholinesterase) required for the synthesis of acetylcholine, a neurotransmitter required for nerve impulse conduction10."

Got that last part?  Let me copy/paste it again:

"Potato saponins can be lethally toxic once in the bloodstream in sufficient concentrations because these glycoalkaloids inhibit a key enzyme (acetyl cholinesterase) required for the synthesis of acetylcholine, a neurotransmitter required for nerve impulse conduction10."

Now let's move over to the subject of Down Syndrome . . .

From http://einstein-syndrome.com/biochemistry_101/cell_biology/, a very informative website regarding Down Syndrome:

"Acetylcholine has many functions in the body, including activation of muscle fiber, release of hormones, and learning/memory. The reason that acetylcholine is of interest to us is that there are fewer acetylcholine receptors in the brain in Down syndrome. It is thought that this contributes to some of the memory and learning problems seen in Down syndrome, because nerves are being stimulated less frequently. Finally, it may explain some of the endocrine (hormone) problems seen in Down syndrome, such as short stature, since release of Growth Hormone is affected by acetylcholine (essentially, the nerves are not talking to the portion of the brain that releases the hormone.) To counter this problem, supplementary choline and inositol is included in the TNI formula. These chemicals are used by the body to make acetylcholine."

not only that . . . but this!
From http://www.dukehealth.org/health_library/news/421:
"Duke University Medical Center researchers tried the Alzheimer's drug on individuals with Down Syndrome because they realized both disorders result, in part, from an insufficient supply of a brain neurotransmitter called acetylcholine."

If all this information is known and readily available . . . WHY am I the only person who seems to have made this connection????  OMFG is all I have to say . . . while beating my head against the wall.

SOMEBODY PLEASE READ THIS AND PASS IT ON!!!

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